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Document Type

Original Article

Abstract

Background: Primary open-angle glaucoma (POAG) is an adult-onset, slowly progressing optic neuropathy characterized by the atrophy of the optic nerve and the death of retinal ganglion cells and their axons over time, The introduction of micro pulse laser trabeculoplasty (MLT) has allowed for the safe and effective treatment of several retinal maculopathies. This is achieved using a duty cycle algorithm that provides subthreshold therapy to ocular tissues without scar formation. Objective: Evaluation of subthreshold (MLT) efficacy in primary open angle glaucoma management. Methods: We conduct a randomized prospective case series study of primary open angle glaucoma cases. Including 40 eyes of patients with primary open angle glaucoma. This research was carried out at Bab El-Sharea University Hospital's Ophthalmology Department. Results: This investigation comprised 40 patients' eyes. Patients mean age was 55.50 ± 6.78 years. 12 patients were males and 28 females. Cup–disc ratio mean pretreatment was 0.56 ± 0.083 all the patients were on medications. Per session, on average, 120 burns were administered. The average pre-intraocular pressure was 19.50 ± 2.26 and the post-laser IOP at 2nd hour post laser, 1st day, 1st week, 4th week, 12th week, 24th week. 18.75, 18.70, 17.20, 16.15, 16.20, 15.90 mmHg respectively. The mean reduction in IOP (%) at the first day, 1week, 4weeks,12 weeks and last follow up was 4.1%, 12%, 17.2%, 16.9%, 18.5%. There is a clinically significant difference between mean the base line IOP and the post laser intraocular pressure at different follow up times except after first day where there are no clinically significant differences. Conclusion: Subthreshold micro pulse trabeculoplasty is a safe procedure has no eye complications. It is effective as an adjuvant treatment in patient with primary open angle glaucoma. As MLT has no eye complications it can be repeated safely if the response is poor after three months or IOP got elevated later. It is effective as a first-line therapy for open-angle glaucoma, especially normal-tension glaucoma.

Keywords

Efficacy of micropulse; Argon laser trabeculoplasty; Primary open angle glaucoma

Subject Area

Ophthalmology

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