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Document Type

Original Article

Abstract

Background: One of most common chronic neurologic disorders is epilepsy. incapability of significantly reduce percentage of studied cases resistant to all available antiepileptic treatments without producing unacceptable side effects is particularly frustrating. Aim & objectives: Aim of research was to investigate seizure result following corpus callosotomy in relation to extent of resection in pediatric studied cases with Symptomatic generalized epilepsy with normal preoperative brain imaging on MRI Brain. Studied cases & Methods: Research entails prospective analysis of data from 20 pediatric patients who were treated for intractable symptomatic generalized epilepsy by corpus callosotomy. Results: In our patient series, 13 patient suffered from genralized tonic clonic fitts (56.3%) and 7 patient is multi focal fitts (43.8%) one of them is Lennox gustate syndrome, No statistical significant variation (p-value = 0.101) among grade II & grade III studied cases as regard presentation, Conclusion: Corpus callosotomy affords a good outcome for drop attacks, at least 70% of patients will experience free from these attacks, a so it will abolish the harmful effects like bodily injury, limited activity and caregivers dependency. In pediatric studied cases, there is no variation in result among total & anterior 2/3 colostomy except some cases may complicate in total colostomy with disconnection syndrome, but anyway these cases show better improvement than adult cases

Keywords

corpus callosotmy; management; drug resistant epilepsy

Subject Area

Neurosurgery

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