Document Type

Original Article


Background: Epithelial thickness mappig can be used adjunctive tool for sensitivity and specificity improvement in early detection of keratoconus screening using Anterior Segment Optical Coherence Tomography. Aim: to detect the role of epithelial thickness mapping in early detection and differentiation between early keratoconus and high regular astigmatism. Patients and Methods: A cross-sectional observational study included 25 eyes of early keratoconus cases and 25 eyes of high regular astigmatism controls conducted at Magrabi Eye Hospital –Tanta between October 2021 and August 2022. Results: our findings revealed that the mean central epithelial thickness was significantly thinner in early keratoconus eyes (49.84 ± 1.95 μm) than that in high regular astigmatism (53.24 ± 3.72 μm) (P value: 0.002). Early keratoconus cases had significantly lower thinnest location (42.92 ± 2.53 μm) compared to high regular astigmatism (46.00 ± 5.17 μm) (P value: < 0.001). Conclusion Measurement of epithelial thickness provided by anterior segment OCT-epithelial-mapping is benificial for early identification of keratoconus .


keratoconus ; Astigmatism; Epithelial mapping; anterior segment OCT.

Subject Area