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Corresponding Author

Mohamed Hussein Mohamed Alashmawi

Document Type

Original Article

Abstract

Background; The aetiology of dry eye disease includes abnormalities in the neurosensory system, ocular surface inflammation, tear film instability, as well as hyperosmolarity (DED), a multifactorial ocular surface condition with absent tear film homeostasis and uncomfortable eyes, Aim and objectives; to detect changes in the tear film in patients of sever dry eye disease (DED) after Autologous serum (AS) using ocular surface analyzer (OSA), Subjects and methods; In this interventional trial, autologous serum eye drops were administered to 10 patient eyes. who presented to the AL-Azhar University's department of ophthalmology with a moderate to severe dry eye disease. Tear .The case went on for six to twelve months, Result; Measurements of the Ocular Surface Disease Index (OSDI) were made both before and during the injection of autologous serum. When using autologous serum, , the OSDI ranged from 18 to 44 with mean SD = 27.7 8.21, having a difference between the two groups that is very statistically significant (p= 0.001). OSDI in Before Autologous Serum measurements ranged from 42 to 87 with mean SD = 69.4 12.88, Conclusion; According to an advancement in OSDI, For the safe and efficient treatment of severe dry eye disease, eye drops containing autologous serum are used.Schirmer's First, LLD, TMH, NIBUT, Tear Film Break-Up Time, and

Keywords

Tear film, Autologous Serum, Dry Eye, ocular surface analyser

Subject Area

Ophthalmology

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