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Corresponding Author

Mostafa Mostafa Mahrouz

Document Type

Original Article

Abstract

Background: Endothelium of the cornea is important for being transparent and this is achieved by its effectiveness in maintaining the dried stroma through two key mechanisms: the active fluid pump and barrier functions, any impairment in those mechanisms may have an impact on clarity.

Aim of the work: To ascertain how phacoemulsification and foldable intraocular lens (IOL) implantation affect the cornea's central thickness and endothelial layer in diabetics compared to controls.

Patients and Methods: A prospective case-control research including 120 eyes is carried out,

to ascertain how phacoemulsification and foldable intraocular lens (IOL) implantation affect the cornea's central thickness and endothelial layer in diabetics compared to controls.

Results: With regard to preoperative data, all patients had a mean age of (59.4 ± 4) years. Regarding gender, 64.2% of patients were female, and 35.8% of patients were male. Regarding DM data, patients had an average disease duration of (13.2 ± 1.7) years, and their average HbA1C was (6.3 ± 0.2) mg/dL. With regard to cataract type, patients had (25.8%) AC, (50.8%) NC, (17.5% PC), and (5.8% PSC).

Conclusion: Phacoemulsification with IOL implantation had a greater effect on diabetics' corneas endothelium layer and central thickness, particularly in reducing postoperative CD and increasing postoperative CCT, which leads to significant endothelial damage in DM patients. Phacoemulsification affects central corneal thickness due to edema of the cornea after phaco, which resolves slowly, but recovery may occur in diabetic patients after a long period.

Keywords

Cornea; Cataract; Specular Microscopy; Diabetes

Subject Area

Ophthalmology

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