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Corresponding Author

Mohamed Ibrahim Mostafa Helmy

Document Type

Original Article

Abstract

Background: Magnesium is a physiological calcium channel blocker and NMDA receptor antagonist. Aim: To compare the impact of applying Mg sulfate with bupivacaine epidural and magnesium sulfate intravenous infusion with epidural anesthesia in females undergoing elective caesarian section.

Patients and Methods: A prospective, randomized blinded clinical trial included 60 women who underwent elective cesarean section conducted in Al-Azhar University Hospital in Cairo from the period from September 2022 to September 2023.

Results: At 90 minutes, 2, 4, 12, 16, 20, and 24 hours, the mean VAS in group II was substantially greater than in group I, with corresponding p values of 0.005, 0.000, 0.002, 0.001, 0.011, and 0.002, 0.000. For patients who needed ketolac supplements, group II's time to first analgesia was substantially shorter than group I's. (p = 0.005). Group II consumed a substantially larger total dosage of analgesics throughout the 24-hour postoperative period than Group I (P = 0.721). Regarding postoperative side effects, there was no statistically substantial variation between the two groups under investigation. Regarding patient satisfaction, there was no statistically substantial variation between the two groups under investigation.

Conclusion: When added to epidural bupivacaine, magnesium sulfate enhanced postoperative analgesia. Magnesium sulfate and epidural bupivacaine may delay the need for first-rescue analgesics.

Keywords

Magnesium sulfate; Epidural; Intravenous; bupivacaine

Subject Area

Anesthesiology

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