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Corresponding Author

Sameh Gamal

Document Type

Original Article

Abstract

Background: Optical Coherence Tomography (OCT) is a non-contact, non-invasive technique that detects the echo magnitude time delay time of backscattered light via low-coherence interferometry.

Aim: To investigate and compare ganglion cell layer thickness between children with refractive error (myopia and hyperopia), helping later-on earlier detection of disorders that possess damaging effects on such layers as glaucoma.

Patients and methods: This cross-sectional observational research was performed on 240 of 120 children attending Al-Azher University hospitals and Port Said Ophthalmology Hospital, Egypt. They were separated into three collections: Group I Involved 80 eyes of children with axial myopia, Group II Involved 80 eyes of children with hyperopia, and Group III Involved 80 eyes of children with emmetropes.

Results: Axial length was highest among the myopic group, 24.15±0.25, than the emmetropic group (22.92±0.33) and hyperopic group (21.8±0.30) with a statistically significant difference (p<0.001). The superior, inferior, and total ganglion cell complex (GCC) layers were thinner among the myopic group than the emmetropic group and hyperopic collection with statistically significant variance (p<0.001). All GCC showed insignificant correlations with age in all collections. There is a significant direct correlation between axial length with (superior GCC, inferior GCC, and total average GCC measurements) in all groups.

Conclusion: There is no discernible correlation between retinal thinning in isolation & the refractive outcome or visual function of individuals., with some studies indicating no relationship between SE and GCC, while others have contradictory findings.

Keywords

GCC; Myopia; Hyperopia; Glaucoma

Subject Area

Ophthalmology

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