Incidence of Methicillin Resistant Staphylococcus Aureus Acquisition in Burn Intensive Care Unit, A meta-analysis study

Authors

AbdElrahman Awadeen AbdElrahman, Department of Plastic and Burn Surgery, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Mohammed Abdel Hamid Basiouny Khedr, Department of Clinical Pathology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Mohammed Abdelsamie El-Zoeiky, Department of Plastic and Burn Surgery, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Ahmed Seliem Hussein Mohammed, Department of Plastic and Burn Surgery, Faculty of Medicine for Boys, Al-Azhar University, Cairo, EgyptFollow

Corresponding Author

Ahmed Seliem Hussein Mohammed

Document Type

Meta Analysis

Abstract

Background: The skin acts as the body's first line of defense against harmful germs.

Aim: To assess the incidence and outcomes of MRSA acquisition in admitted patients within burn ICU in the last ten years.

Patients and methods: The current meta-analysis involved 16 articles with a total of 7623 individuals, the majority of these studies were retrospective and only four studies were prospective most of these studies were from USA and China, and no studies from Egypt were found, so more prospective studies were needed to be performed among ICU burn patients in Egypt.

Results: In all, four studies examined the effect of MRSA on mortality rate. No significant heterogeneity was determined. Therefore, a fixed effect model was utilized for analysis (I² = 0%, P =.56). The combined OR & 95% CIs was 1.28 (0.69 to 1.40). The combined result suggested that MRSA-positive patients are not associated with a higher mortality rate (Z = 0.78, P =.44).

Conclusion: The study found 14.7% MRSA infections in burn patients admitted to burn ICUs, with 3.8% colonization and 8.6% acquisition. Risk factors include age, burn surface area, male gender, inhalational injury, and burn cause.

Keywords

Staphylococcus Aureus; Methicillin Resistant; Acquisition; burn intensive care unit

Subject Area

Plastic surgery

How to Cite This Article

AbdElrahman, AbdElrahman Awadeen; Khedr, Mohammed Abdel Hamid Basiouny; El-Zoeiky, Mohammed Abdelsamie; and Mohammed, Ahmed Seliem Hussein (2024) "Incidence of Methicillin Resistant Staphylococcus Aureus Acquisition in Burn Intensive Care Unit, A meta-analysis study," Al-Azhar International Medical Journal: Vol. 5: Iss. 8, Article 20.
DOI: https://doi.org/10.58675/2682-339X.2596