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Corresponding Author

Alaa Mohamed Elmesiry

Document Type

Original Article

Abstract

Background: Post traumatic scars remain a nightmare for both the patient and the surgeon. Nanofat is a new tool used in regenerative medicine its action depends mainly on adipose derived stem cells (ADSCs). ADSCs play an important role in scar rejuvenation. Platelet-rich plasma is an advanced scar therapy that has shown positive alteration in the treatment of scars through the highly concentrated autologous platelets that release numerous growth factors, cytokines, and fibrin, which may be valuable in improving the whole scar quality.

Objective: To compare nanofat and PRP injections in recent scar treatment.

Patients and Methodology: This prospective randomized clinical study included 20 patients divided into two equal groups: Group (A): Post traumatic scar treated by nanofat injection. Group (B): post traumatic scar treated by PRP injection. Their ages ranged between 18 and 40 years. The duration of the scar varied between 1 and 6 months.

Results: The results of this study showed higher cosmetic improvement and patient satisfaction in group (A) treated by nano fat injection versus group (B) treated by PRP injection. There was a highly significant improvement in scar height, Pigmentation, and vascularity when comparing group (A) to group (B), but scar pliability improved equally in both groups.

Conclusion: Nano fat and platelet-rich plasma (PRP) are reliable tools in dealing with recent post-traumatic scars. Patients treated with nonfat injection showed much improvement in scar height, Pigmentation, and vascularity compared to PRP-treated patients.

Keywords

Adipose-derived stem cells; Growth factors; nanofat; PRP

Subject Area

Plastic surgery

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