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Corresponding Author

Mohamed Maher Mohamed Ali

Document Type

Original Article

Abstract

Background: The prevalence of diabetes (DM) is increasing worldwide. Microvascular complications like diabetic retinopathy and neuropathy are very likely to occur in diabetic patients.

Aim: To assess capillary plexuses and the foveal avascular zone (FAZ) in diabetic cases without clinical maculopathy using OCTA.

Patients and methods: This observational study was conducted on ninety eye cases at an outpatient clinic in the Ophthalmology Department of Sayed Galal University Hospital from May 2022 to January 2023. cases were divided into two groups: thirty eyes in ordinary people and sixty eyes in patients with diabetes, who were divided into two subgroups: group (a) involved thirty eyes with DM cases without DR, and group (b) included 30 eyes with non-proliferative diabetic retinopathy.

Results: There was a significant variance among groups regarding BCVA. There was no significant variance regarding IOP and CMT (p > 0.01). There was a high significant variance among groups regarding SCP% and DCP% (p<0.001). There was also a significant variation in FAZ in SCP and IN DCP (p = 0.01). Significant correlations were among FAZ and cholesterol, TG, and HbA1c (p<0.0001). At the same time, FAZ and IOP had an insignificant association (p > 0.01).

Conclusion: OCTA is a noninvasive method that can help diagnose and monitor eyes with DR. OCTA was used to identify enlargement of the FAZ and accurately delineate the edges of these zones in SCP & DCP in DM cases without clinical maculopathy.

Keywords

Macula; Diabetic patients; Optical coherence tomography angiography

Subject Area

Ophthalmology

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