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Corresponding Author

Islam Hamdy Awad Gad El-Demohy

Document Type

Original Article

Abstract

Background: Diabetes is a long-term metabolic disease marked by elevated blood sugar values. People all around the globe suffer from it often, and those who have end-stage renal disease (ESRD) are more likely to have it.

Aim and objectives: To examine the relationship between diabetic dialysis patients' HbA1c levels and cardiovascular events.

Patients and methods: This prospective observational and analytical research was conducted on 60 diabetic patients on hemodialysis at the dialysis Unit of the National Institute of Urology and Nephrology, Egypt.

Results: The mean HBA1C was statistically substantially more significant in the cases with cardiovascular complications as compared to the cases without cardiovascular complications. The prevalence of cases with uncontrolled diabetes was statistically substantially more significant in the cases with cardiovascular complications as compared to the cases without cardiovascular complications. The best cutoff point of HbA1C to differentiate the occurrence of cardiovascular complications was > 8.15 %, with 84.6 sensitivity and 614% specificity. The AUC was 0.709, with a statistically substantial value. The incidence of Myocardial infarction, PAD, and heart failure was statistically more significant in the cases with uncontrolled diabetes as compared to the cases with controlled diabetes.

Conclusion: Cardiovascular complications up to death are frequent in diabetic patients on hemodialysis. Uncontrolled diabetes mellitus (represented by elevated HbA1C) is associated with a greater prevalence incidence of complications in diabetic patients on hemodialysis. Adequate and timely diagnosis and treatment of cardiovascular complications could improve the quality of life and postpone complications in these patients.

Keywords

Cardiovascular Complication; ESRD; Hemodialysis

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