•  
  •  
 

Corresponding Author

Mohamed Shawky Mohamed

Document Type

Original Article

Abstract

Background: The ideal approach for myocardial preservation during ischemic cardiac arrest remains controversial. One dosage of cardioplegia for preservation of the myocardium is advocated in protracted surgeries.

Aim: To explore the effects of Bretschneider cardioplegia and warm blood cardioplegia on myocardial protection in patients with ischemic mitral regurgitation following coronary artery bypass graft surgery with mitral valve replacement.

Patient and Methods: This prospective study included 60 patients from the cardiothoracic surgery department at El-Hussein University Hospital and the National Heart Institute. The patients were divided into two groups: (A) thirty patients received Bretschneider cardioplegia, and (B) thirty patients received warm blood cardioplegia. Data from both groups were assembled and compared.

Results: The mean CPB time in the Bretschneider group was 103.67 ± 30.57, while in the warm blood cardioplegia group, it was 121.73 ± 33.98 minutes. The mean of intensive care unit stays in the Bretschneider group was 2.70 ± 0.75 days, whilst in the warm blood cardioplegia group was 3.40 ± 1.07 days, the mean period of the mechanical ventilation in the Bretschneider group was 7 (6 – 9) while in warm blood cardioplegia group was 12 (10 - 18) hours. Troponin elevated: The Bretschneider group was in 3 patients (10%), while the warm blood group was in 19 patients (63.3%).

Conclusion: Bretschneider's cardioplegia solution showed superiority in myocardial protection, reducing CPB and CCT, fewer inotropes used, less mechanical ventilation time, and less elevation of cardiac enzymes, resulting in reduced ICU and hospital stay.

Keywords

Cardioplegia; Bretschneider; Warm blood; myocardial protection; Ischemic Mitral Regurgitation

Subject Area

Thoracic and cardiovascular surgery

Download

Share

COinS