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Corresponding Author

Mohamed Ahmed Tolba

Document Type

Meta Analysis

Abstract

Introduction: Insomnia poses a significant challenge for individuals with rheumatoid arthritis (RA), impacting their daily lives. We address insomnia in RA patients, considering the multifaceted factors contributing to disrupted sleep patterns, such as pain, inflammation, and psychological aspects.

Aim of the work: To identify the frequency of insomnia in patients with rheumatoid arthritis. This study is a crucial step toward understanding and addressing the sleep challenges faced by RA patients.

Methods: In accordance with PRISMA guidelines, we systematically searched databases like PubMed, Web of Science, and Scopus. Eligible studies, identified through screening and quality assessments, were subjected to data extraction. We employed random and fixed effects models to assess heterogeneity and potential publication bias.

Results: The literature search yielded 1,117 articles, with ten studies meeting the inclusion criteria. The prevalence of diagnosed insomnia in RA patients was notably high at 45%, significantly surpassing that of the general population (5.6%). Subgroup analyses addressed heterogeneity, indicated by an I2 value of 99.85%. The study's robust methodology and adherence to PRISMA guidelines contribute to its academic credibility.

Conclusion: This research underscores the frequency of insomnia in RA patients (45%), emphasizing the demand for heightened awareness and efficient screening tools. The potential impact of this study is significant, as it advocates for referral to specialized sleep clinics for tailored interventions, presenting an avenue for mitigating future comorbidities and addressing inflammation-related indicators.

Keywords

Insomnia; rheumatoid arthritis; sleep disturbance

Subject Area

Rheumatology and Medical Rehabilitation

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