Document Type
Original Article
Abstract
Background: It is thought that many primary malignant, benign, and metastatic localized lesions share the liver as a location. In order to avoid inoperable tumors being falsely graded and cases with such tumors being scheduled for surgical treatments, accurate diagnosis and characterization of these tumors are essential pre-treatment steps. For individuals at high risk for complications following a biopsy, diffusion-weighted imaging (DWI) may be an ideal non-invasive way to assess particular tissue characteristics.
Objective: To determine how useful diffusion-weighted magnetic resonance imaging (DWI) was for identifying and characterizing hepatic focal lesions (HFL) that were associated with portal vein thrombosis.
Patients and methods: This prospective descriptive study will be done on 50 patients with pathological or radiological proof of focal liver lesion correlated with visible portal vein thrombosis to assess the role of DWI in the detection and characterization of HFL and associated portal vein thrombosis.
Results: Regarding diffusion-weighted MRI in characterization of HFL with PVT, cases with malignant focal lesions had significantly lower mean apparent diffusion coefficient (ADC) when contrasted to cases with benign focal lesions (0.96 ± 0.17 vs 1.88 ± 0.60; P<0.001), and among patients with malignant focal lesions, patients with malignant PVT had significantly lower mean ADC PVT (1.08 ± 0.16 vs 2.07 ± 0.13; P<0.001), as well as significantly lower ADC ratio (1.07 ± 0.07 vs 2.42 ± 0.50; P<0.001) when contrasted with cases with benign PVT.
Conclusion: DW-MRI is a dependable modality for differentiating benign focal liver lesions from malignant ones. The characteristics of the portal vein thrombus can also be ascertained by calculating the ADC ratio between the thrombus and the tumor.
Keywords
Diffusion weighted MRI; ADC; hepatic focal lesions; Portal vein thrombosis
Subject Area
Radiology & Radiodiagnosis
How to Cite This Article
Sonbel, Mostafa Fadel; Alkenawy, Mohamad Abdel-Rahman; Abdelrahman, Ali Elsaid; and Abdel-Fattah, Abdel-Fattah Gomaa
(2024)
"The role of Diffusion Weighted MRI in Evaluation of Neoplastic Hepatic Focal Lesions in Cases of Portal Vein Thrombosis,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
6, Article 39.
DOI: https://doi.org/10.58675/2682-339X.2499
