Document Type
Original Article
Abstract
Background: In the second trimester, approximately ten percent of first-time mothers will experience the very common pregnancy condition known as pre-eclampsia. Serious, potentially harmful effects on both mother and child are associated with the disorder.
Objective: To evaluate the predictive role of serum arginine level and platelet volume in the prediction of preeclampsia.
Patients and Methods: Outpatient gynecology and obstetrics clinics at Al Azhar University Hospitals were the sites of this prospective observational study, which is a type of comparative case-control research. One hundred pregnant women participated in our study. Pregnancies involving pre-eclampsia (n = 50) were included in Group A of the participants. Hypotensive pregnancies (n = 50) made comprised Group B. Six to twelve months was the time frame of the study.
Results: The L-arginine was found to be an excellent predictive test where the area under the curve (AUC) equaled 0.960 ± 0.017 (95% CI, 0.927; 0.992), and the P value was .050 (statistically significant). At a cut-off point of 71 μM, the test was found to have a sensitivity of 94% and a specificity of 86%; a receiver operating characteristic (ROC) analysis was carried out to demonstrate the predictive value of MPV (mean Platelet Volume) & L-arginine.
Conclusion: Pregnancies complicated with pre-eclampsia had higher MPV and lower levels of serum L-arginine. The MPV was found to be a good predictor of PE. L-arginine was found to be an excellent predictor of PE.
Keywords
Pre-eclampsia; mean Platelet Volume; Serum Arginine
Subject Area
Obstetrics and Gynecology
How to Cite This Article
Mohamed, Ashraf Hamdy; Saeed, Ahmed Mohamed; and Hassan, Mohallal Ahmed
(2024)
"Serum Arginine Level and Platelet Volume in Prediction of Preeclampsia,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
6, Article 23.
DOI: https://doi.org/10.58675/2682-339X.2483
