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Corresponding Author

Ayman Mohamed Abd-El Aziz

Document Type

Original Article

Abstract

Background: Cesarean section (CS) delivery is the most significant risk factor for postpartum maternal infection, with thirty percent incidence rates of surgical site infection (SSI) reported after CS. Wound healing failure caused by SSI results in increased treatment costs, prolonged hospital stays, and higher postoperative mortality rates.

Aim and Objectives: To investigate the role of subcutaneous Fusidic acid instillation for prophylaxis against SSI in cesarean section.

Subjects and Methods: This prospective randomized controlled clinical research was performed on 150 Pregnant women of reproductive age between 18-40 years with term pregnancy and normal weight for CS in Al-Azhar University Maternity Hospital from the period between 1st January 2022 to June 2022.

Results: There was a statistically significant difference in lower rate of infection, endometritis, and fever in a patient who received fusidic acid than those who did not receive fusidic acid.

Conclusion: Subcutaneous fusidic acid was applied prior to skin closure utilizing absorbable stitches, and the infection rate was nearly six times lower than in the control group. Subcutaneous instillation of fusidic acid is safe and effective in preventing SSI and can be suggested for use in the prevention of wound infections.

Keywords

Cesarean Section (CS), Surgical Site Infection (SSI), Subcutaneous fusidic Acid

Subject Area

Obstetrics and Gynecology

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