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Corresponding Author

Mohammad Mounir Ahmed Rizk

Document Type

Original Article

Abstract

Background: In industrialized nations, 20 to 50% of people have H pylori, whereas in developing nations, 80% of people have the infection. Globally, H. pylori is a major source of disease and death. A number of disorders, including iron deficiency anemia, pancreatic cancer, gastritis, stomach ulcers, and gastric cancer, have been linked to H. pylori infection, according to numerous recent research.

Aim of the work: Reveal the prevalence of H. pylori infection in patients with stomach pathology and figure out the connection between those patients' H. pylori infection and their blood types (Lewis and ABO).

Patients and methods: This descriptive observational study involved 66 patients with a range of gastrointestinal symptoms who visited the endoscopy unit at Al-Hussin University Hospital. All of the participants in the study had gastric biopsy cultures for H pylori. All patients also had stool H pylori Ag, Lewis factor, ABO, and Rh tests performed.

Results: The study was conducted on 66 patients; 40 patients (60.6%) were positive for H pylori by gastric biopsy culture. Fast food outdoor eating, blood group O, blood group B, and Lewis B were predictive for positive gastric biopsy culture. Rifampicin, Levofloxacin, ofloxacin, and tetracycline gave the best sensitivity results compared to amoxicillin, metronidazole, and clarithromycin.

Conclusion: The study validates the link between blood group and H. pylori infection. Individuals with blood group O and Lewis factor B should exercise extra caution to prevent the illness from spreading since they have a higher risk of developing gastritis, ulcers, as well as punctures.

Keywords

pylori; ABO; Lewis factor

Subject Area

Clinical Pathology

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