Potential Role of Subclinical Hypothyroidism in Carpal Tunnel Syndrome Patients (Case Control Study)
Document Type
Original Article
Abstract
Background: It is debatable how subclinical hypothyroidism affects peripheral nerves. The most prevalent type of nerve entrapment neuropathy, known as carpal tunnel syndrome (CTS), is brought on by compression of the median nerve at the wrist as it travels through the carpal tunnel, an osseo fibrous canal.
Aim: To estimate the potential association between subclinical hypothyroidism and CTS patients without a definite risk factor.
Patients and Methods: Over six months, individuals with CTS symptoms who visited the neurophysiology unit at Al-Azhar University Hospitals for an electrodiagnosis were the subjects of this case-control research. The study was carried out in two groups. Case Group: 30 CTS patients without definite risk factors; thirty healthy individuals matched for age and sex but did not exhibit any clinical indications or symptoms of CTS made up the control group.
Results: Regarding subclinical hypothyroidism and euthyroidism, there was a significant difference between the control and case groups (X2= 5.45, p-value = 0.019). Thyroid-stimulating hormone (TSH) levels in the control and case groups differ statistically significantly (p=0.001). The Boston Scoring Symptoms (BSS) and TSH readings have a significant positive link (correlation coefficient: 0.588; p < 0.001). However, no relationship was discovered between the TSH levels and the Boston Scoring Functions (BSF) (p = 0.347) or the Padua's scale CTS severity grading (P = 0.284).
Conclusion: Subclinical hypothyroidism CTS patients with no apparent risk factors are highly associated.
Keywords
CTS; TSH; Padua’s scale; Subclinical hypothyroidism
Subject Area
Neurology
How to Cite This Article
EL Gharieb, Hussein Awad; Fayed, Abdel-Ghaffar Ismail; Shaheen, Mohamed Ahmed; and Dighem, Mohamed Ahmed
(2024)
"Potential Role of Subclinical Hypothyroidism in Carpal Tunnel Syndrome Patients (Case Control Study),"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
5, Article 7.
DOI: https://doi.org/10.58675/2682-339X.2409