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Corresponding Author

Ahmed Ismail Abd El Rahman Khater

Document Type

Original Article

Abstract

Background: The global epidemic of morbid obesity compelled modern medicine to take a multifaceted strategy, which resulted in the identification of metabolic syndrome (MS), one of the biggest causes of morbidity and death and a condition with self-aggravating elements. Metabolic surgery was developed in response to the demand for therapeutic approaches, providing opportunities for the safe and efficient treatment of all components of multiple sclerosis at the same time.

Aim and Objectives: To assess how laparoscopic sleeve gastrectomy affects obese patients' metabolic syndrome parameters.

Subjects and Methods: The present research is a prospective cohort investigation of fifty patients who underwent laparoscopic sleeve gastroplasties (LSGs) at the Al-Azhar University Hospital's General Surgery Department between January 2018 and January 2020. All patients were monitored for the third, sixth, and twelve months following surgery. In this investigation, all relevant guidelines and bioethical recommendations were followed.

Result: The median age of the patients was 48, with a range of (42-58) years. About two-thirds were females (62%). 78% percent were hypertensive, and 54% were diabetics before surgery. At 12 months follow-up, significant improvements regarding all parameters were observed. A total reduction of 37 mg/dl in median glucose concentration was achieved, HbA1C dropped to 5.6 compared to 6.7 preoperatively, complete diabetes remission was observed in 44.4% of patients, 59% of the hypertensive patients were self-regulated, body mass index dropped from 49.2 to 32.4 kg/m2, patients lost 70% of their excess weight. Additionally, there was a large rise in high-density lipoproteins and a significant decrease in triglycerides, total cholesterol, and low-density lipoproteins.

Conclusion: For comorbidities associated with obesity and metabolic syndrome, LSG is a useful treatment.

Keywords

Laparoscopic Sleeve Gastrectomy, Metabolic Syndrome, Obesity

Subject Area

Obstetrics and Gynecology

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