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Corresponding Author

Fathy Abdel-Halim Mohamed

Document Type

Original Article

Abstract

Background: The fluid challenge test is a prominent method for determining fluid responsiveness in patients with acute circulatory failure. An easy method will be tested to detect the patient's response to the fluorimetry-derived using pa, oximetry-derived peripheral pe, and fusion index.

Objective: To evaluate: whether pulse oximetry-derived peripheral perfusion index may predict fluid responsiveness in septic shock patients.

Subjects and Methodology: A prospective cohort research was conducted on 35 septic shock patients requiring fluid resuscitation to compare LVOT VTI variability and PPI for assessing fluid responsiveness. After baseline measurements, we administered a mini fluid challenge of 200ml crystalloids. Fluid responsiveness was characterized as a greater than 10% increase in LVOT VTI.

Results: From 35 patients who were admitted, 26 (74.3%) were fluid responsive and (25.7%) 9 were not responsive; peripheral perfusion index (PPI) had a statistically significant correlation with Meanleft ventricular outflow tract velocity time integral(LVOT VTI) variability.

Conclusion: PPI measured by pulse oximetry is noninvasive, inexpensive, and extremely reliable for estimating fluid responsiveness in critically ill patients with hypoperfusion symptoms. It outperforms LVOTVTI estimations from transthoracic echocardiography. Dynamic PPI trends enable real-time fluid responsiveness-guided patient-tailored early resuscitation.

Keywords

Background: The fluid challenge test is a prominent method for determining fluid responsiveness in patients with acute circulatory failure. An easy method will be tested to detect the patient's response to the fluorimetry-derived using pa, oximetry-derived peripheral pe, and fusion index. Objective: To evaluate: whether pulse oximetry-derived peripheral perfusion index may predict fluid responsiveness in septic shock patients. Subjects and Methodology: A prospective cohort research was conducted on 35 septic shock patients requiring fluid resuscitation to compare LVOT VTI variability and PPI for assessing fluid responsiveness. After baseline measurements, we administered a mini fluid challenge of 200ml crystalloids. Fluid responsiveness was characterized as a greater than 10% increase in LVOT VTI. Results: From 35 patients who were admitted, 26 (74.3%) were fluid responsive and (25.7%) 9 were not responsive; peripheral perfusion index (PPI) had a statistically significant correlation with Meanleft ventricular outflow tract velocity time integral(LVOT VTI) variability. Conclusion: PPI measured by pulse oximetry is noninvasive, inexpensive, and extremely reliable for estimating fluid responsiveness in critically ill patients with hypoperfusion symptoms. It outperforms LVOTVTI estimations from transthoracic echocardiography. Dynamic PPI trends enable real-time fluid responsiveness-guided patient-tailored early resuscitation.

Subject Area

Emergency and ICU medicine

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