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Corresponding Author

Tarek Mohamed M. Mansour

Authors ORCID

https://orcid.org/0000-0001-7074-9939

Document Type

Original Article

Abstract

Background: Allergic fungal sinusitis (AFS) is a non-invasive sinusitis that typically affects young people.

Aim and objectives: To explain the potential risk factors that may affect patients suffering from nasal polyps with AFS local anatomical variants or general illnesses.

Methods: This case-control study was conducted on 160 patients who were divided into case & control groups. Eighty patients with AFS with nasal polyposis( case group) and 80 cases with nasal polyp without superimposed fungal infection ( control group ). All participants were evaluated clinically by laboratory investigation (vitamin D level, HbA1c) and radiologically (computed tomography (CT) and chest x-ray) to look for signs of sinusitis, turbinate hypertrophy, nasal septal deviation, conch bullosa, minimal width of infundibulum (MW-I), and maximal length of infundibulum (ML-I).

Results: The mean vitamin D level was considerably lower in the case group (27.86 ±5.92) ng/mL) than in the control group (38.98 ±5.92) ng/mL). The cases had significantly higher anatomical abnormalities (deviated nasal septum and inferior turbinate hypertrophy) than the control group (P value

Conclusions: Features of anatomical abnormalities, such as a notably deviated septum, MW-I, and ML-I, may increase the incidence of fungal sinusitis more than general illnesses such as bronchial asthma and DM. Vitamin D deficiency may play a role in developing superimposed fungal sinusitis.

Keywords

Allergic fungal sinusitis; Risk factors, vitamin D; computed tomography

Subject Area

Radiology & Radiodiagnosis

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