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Corresponding Author

Mahmoud Ali Salem Abu Alrabegi

Document Type

Original Article

Abstract

Background: Avascular necrosis of the femoral head(ANFH) is brought on when there is a disruption in the blood flow to the affected area. This leads to the death of cells in the trabecular bone and the marrow. This condition manifests as advanced osteoarthritis and subsequent surface collapse.

Aim and objectives: To examine the clinical and radiological results of treating early avascular necrosis with core decompression combined platelet-rich plasma.

Subjects and methods: This randomized clinical research was carried out on 30 individuals presenting with ANFH attending Orthopedic Clinics of Al-Hussein Hospital, Al-Azhar University, Cairo-Egypt. 4 Patients were bilateral and 26 patients unilateral patients divided into two groups: group A involved 15 cases received platelets rich plasma PRP following core decompression and group B (control group) involved 15 cases who received normal saline following core decompression from September 2022 until October 2023.

Result: Group A comprised individuals aged 26 to 38 years, with a mean age of 31±3. With a range of 26 to 40 years, group B comprised individuals with an average age of 33 ± 4 years. Group A demonstrated significantly better modified Kerboul Angle and Ficat and Arlet stage than group B at the last follow-up (P < 0.05).

Conclusion: PRP following CD for early-stage ANFH reduced pain and improved functional results. The PRP group had a significantly reduced rate of disease development measured by both necrosis & collapse.

Keywords

Outcome; Core Decompression; Platelet Rich Plasma; Early Avascular Necrosis

Subject Area

Orthopedics

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