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Corresponding Author

Ashraf Mohammad Hasan Sherif

Document Type

Original Article

Abstract

Background: Sudden sensorineural hearing loss (SSNHL) is a sudden, often unilateral hearing impairment with unclear causes. An intratympanic dexamethasone injection is a treatment option, delivering anti-inflammatory benefits directly to the inner ear with fewer side effects. Platelet-rich Plasma (PRP) therapy is an innovative approach that enriches blood plasma with growth factors, promoting inner ear hair cell health and hearing improvement. Both treatments offer hope for those with SSNHL.

Aim of the work: To examine the effectiveness of intratympanic platelet-rich plasma (PRP) injections and Dexamethasone in treating sudden sensorineural hearing loss (SSNHL).

Patients and methods: 30 patients with SSNHL participated in this study. They were divided into two equal groups: group A received PRP intratympanic injection, and group B received Dexamethasone intratympanic injection. Pure tone audiometry (PTA) was done before and after injection to assess hearing improvement at 500Hz and 2000Hz.

Results: In the dexa group, the hearing threshold improvement(Mean±SD) was 10.33±19.04 dB and 16 ± 20.02 dB at 500Hz and 2000Hz, respectively, while in the PRP group, the hearing threshold improvement (Mean±SD)was 20±17.32 dB and 22.2 ±21.36 dB at 500Hz and 2000Hz respectively.

Conclusions: There are no significant differences between PRP and dexamethasone groups; both treatments have shown potential efficacy in improving hearing outcomes in SSNHL. Further research and larger studies are needed to establish the effectiveness and optimal protocols for PRP injections in SSNHL treatment.

Keywords

SSNHL; SSHL; Dexamethasone; PRP; Intratympanic injection

Subject Area

ENT

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