Document Type
Original Article
Abstract
Background: The combination of oral nifedipine and transdermal nitroglycerine is an effective method for managing premature labor. Tocolysis plays a critical function in preterm labor cessation.
Aim: To assess the efficiency of dermal patches containing nifedipine, magnesium sulfate, and nitroglycerine in the management of premature labor.
Patients and methods: This is a randomized controlled research performed on 150 preterm labor women receiving nifedipine, magnesium sulfate and nitroglycerine who attended the Department of Gynecology and Obstetrics at El Hussein University Hospital during the period from January 2022 to February 2023.
Results: In terms of birth weight and gestational age at delivery, group II significantly increased more than groups III and I.Furthermore, group I experienced a significantly longer NICU stay than groups II and III. In contrast to groups II and III, inpatient admissions to the NICU and respiratory distress in infants were more prevalent in group I. Although there was no significant distinction identified among the groups analyzed with regard to infant fatalities, hemorrhage, bleeding, or modes of delivery, group II exhibited a higher incidence of CS in contrast to groups I and III, and group III had a higher incidence of NVD than groups I and II. In comparison to groups I and II, group III exhibited the highest frequency of PROM.
Conclusions: For the treatment of preterm labor, oral nifedipine is a good substitute for magnesium sulfate, having the same effectiveness and adverse effects.
Keywords
Dermal patch; Magnesium sulphate; Nifedipine; Nitroglycerine; Preterm labour
Subject Area
Obstetrics and Gynecology
How to Cite This Article
kassab, Farid Ahmed; Ibrahim, Mohamed Ibrahim Mohamed; and Alfeky, Ahmed Adel Ali
(2024)
"Role of Nifedipine, Magnesium Sulphate and Nitroglycerine Dermal Patch in Preterm Labour,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
4, Article 24.
DOI: https://doi.org/10.58675/2682-339X.2368
