Document Type
Original Article
Abstract
Background: Surgical options for Parkinson's disease (PD) consist of ablative procedures and deep brain stimulation (DBS). The targets for ablation are the VIM, the globus pallidus, and the subthalamic nucleus.
Aim: To assess efficiency, complications & safety of variable targets in ablative surgery in Parkinsonian disease.
Methods: This Retrospective research was conducted on 20 Parkinsonian individuals in 2022. All patients were subjected to the Unified PD Rating Scale (UPDRS), with special attention to the motor score (part III).
Results: This study demonstrated improvement in the Unified PD Rating Scale (UPDRS) between preoperative and 6-month postoperative motor symptoms in twenty patients. There were very statistically substantial ( P-value < 0.01), which is highly significant; there was a significant decrease in (UPDRS) from preoperative (40.30 ± 13.48) to 6 months postoperative (12.85± 7.73) as regards Chi-square test and Fisher exact test for comparison of two groups with qualitative data and Independent t-test for comparison between two independent groups with quantitative data and parametric distribution.
Conclusions: Ablative surgery can be considered a safe & effective therapy option for PD.
Keywords
Ablative Surgery; Different Targets; Parkinsonian Disease
Subject Area
Neurosurgery
How to Cite This Article
Al Aghory, Islam Mohammed; Ibrahim, Alaa Rashad; and Zaki, Ahmed Adel
(2024)
"Different Targets in Ablative Surgery in Management of Parkinsonian Disease,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
4, Article 22.
DOI: https://doi.org/10.58675/2682-339X.2366
