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Corresponding Author

Ammar Sharaf Mahmoud Ahmed

Document Type

Original Article

Abstract

Background: Low serum T3 and T4 levels can be caused by hormone loss during dialysis, decreased T3-binding capacity, serum thyroid autoantibodies, altered hormonal catabolism, increased thyroid iodine storage, and impaired peripheral conversion.

Aim and objectives: To investigate thyroid function tests and their correlation with serum iodine levels in patients on regular hemodialysis.

Subjects and methods: This prospective cross-sectional trial involved 100 cases of hemodialysis selected from attendees at Al-Azhar University Hospitals and Fayoum General Hospital. Participants were divided into two groups.

Results: There was no substantial variance amongst the two investigated groups concerning gender, age, and BMI. There was a statistically significant distinction in TSH, free T3, and free T4 across the two groups; however, there was no distinction in iodine. Free T4 and free T3 levels were positively and significantly correlated with iodine. Meanwhile, there is a significant negative association between iodine and TSH.

Conclusion: Our study revealed that, despite the significant variation among the two groups concerning TSH, free T3, and free T4, there was no significant difference regarding iodine level, and there was a significant positive correlation among iodine values with free T4 and free T3 but not TSH.

Keywords

Thyroxine (T4); Triiodothyronine (T3); Thyroid stimulating hormone(TSH); Iodine; Hemodialysis patients

Subject Area

Internal Medicine

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