Document Type
Original Article
Abstract
Background: Nailfold capillaroscopy (NFC) represents the best method to analyze microvascular abnormalities among connective tissue diseases (CTDs) since capillaroscopic changes of the nailfold have been well established in many CTDs Aim: to investigate serum IL-17 and Nailfold microcirculation in RA and SLE patients and to study their correlation with disease activity in upper Egypt. Patients and Methods: A total of 50 patients with RA and 30 patients with SLE. In addition to, 30 healthy subjects as control group. Results: Patients with either SLE or RA had significantly higher IL-17 in comparison to the control group. Patients with SLE had significantly higher frequency of Bushy capillaries elongated capillaries, enlarged capillaries, subpapillary plexus, disorganized capillaries, haemorrhage and avascular area in comparison to control group. Patients with RA had significantly higher frequency of bushy capillaries while patients with SLE had significantly higher frequency of elongated capillaries, disorganized capillaries, haemorrhage and avascular area. Conclusion: SLE or RA patients had significantly higher IL-17 in comparison to the control group. NFC, patients with RA had significantly higher frequency of bushy capillaries while patients with SLE had significantly higher frequency of elongated capillaries, disorganized capillaries, haemorrhage and avascular area.
Keywords
Nailfold capillaroscopy; Rheumatoid arthritis; Systemic lupus erythematosus
Subject Area
Internal Medicine
How to Cite This Article
AbdelKareem, Mohamed I.; Rayan, Mohamed M.; and Sayed, Ashraf I.
(2024)
"Nail Fold Capilloroscopy Versus Serum interleukin 17 in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients and their Correlation with Disease Activity in Upper Egypt,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
3, Article 7.
DOI: https://doi.org/10.58675/2682-339X.2321
