Document Type

Original Article


Background: Systemic sclerosis (SSc) is a disease of unknown etiology characterized by tissue fibrosis and microvascular abnormalities. Microvascular damages of the hand can easily be evaluated using nailfold capillaroscopy (NFC). Aim: To evaluate the relationship between microvascular damages assessed by Nailfold capillaroscopy and macrovascular features evaluated by Doppler Ultrasound to assess the severity of hand involvement and vasculopathy in Systemic Sclerosis. Methods: This study was carried out on 50 adult patients with progressive SSc. Results: According to Nailfold Capillaroscopy findings, 9 (18%) patient diagnosed as early phase of SSc while 24 (48%) patients were at late phase and 17 (34%) patients showed active disease. We used PDUS after NFC for detecting incidence of pathological FPBF and UAO. We found that 24 (48%) patients showed UAO and 29 (58%) patients showed pathological FPBF. According to association between ultrasonography / nailfold capillaroscopy findings and other parameter assess the severity of vasculopathy. There was a significant association between presence of (Raynaud’s phenomena, Pitting scar, Digital ulcer, acroosteolysis and Calcinosis) and ultrasonography / nailfold capillaroscopy findings (p


Ultrasonography, Nailfold Capillaroscopy, Systemic Sclerosis, Vasculopathy