Dynamics of iron profile in Helicobacter pylori infection before and after eradication

Authors

Mahmoud Abd Al Rasheed Abd Al Khaleq, Department of Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Abdelaleem Abdelaleem Aly Elgendy, Department of Clinical Pathology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Mohamed Aly Abdelkhalek Alboraie, Department of Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Mohamed Hassan Ahmed Negm, Department of Internal Medicine, Faculty of Medicine for Boys, Al-Azhar University, Cairo, EgyptFollow

Abstract

Background: It has been observed that infection with Helicobacter pylori (H. pylori) is the leading cause of both mortality & morbidity in cases of upper gastrointestinal (GI) illnesses. There is a dearth of studies examining the link between H. pylori & iron deficiency anemia (IDA). Aim and objectives: to assess dynamics of iron profile in cases suffering from H.pylori infection before & after (6 weeks) eradication treatment. Subjects and methods: This Prospective cohort Pre-Post test research was carried out in the the internal medicine department in gastroenterology & hematology units (inpatients and outpatients), 106 patients diagnosed with Helicobacter pylori infection were enrolled in this research. Results: there was great statistically significant variance among Hb, MCV, MCH & PLTs before and after treatment, there was statistically significant variance among WBCs before & after therapy. There was high statistically significant variance among iron profile before & after therapy. Conclusion: we concluded that The incidence of anemia, especially iron deficiency anemia, varied greatly before and after the course of therapy and elimination of H. pylori infection

Article Type

Original Article

Keywords

ferritin; iron profile; serum iron level; TIBC H. Pylori infection.

Subject Area

Internal Medicine

How to Cite This Article

Khaleq, Mahmoud Abd Al Rasheed Abd Al; Elgendy, Abdelaleem Abdelaleem Aly; Alboraie, Mohamed Aly Abdelkhalek; and Negm, Mohamed Hassan Ahmed (2024) "Dynamics of iron profile in Helicobacter pylori infection before and after eradication," Al-Azhar International Medical Journal: Vol. 5: Iss. 2, Article 33.
DOI: https://doi.org/10.58675/2682-339X.2250