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Document Type

Original Article

Abstract

Background: Since its invention in the 1950s, laser photocoagulation has been the standard therapy for diabetic retinopathy (DR). Historically, retinal photocoagulation has made use of wavelengths between 400 and 800 nm.

Objectives: to investigate the impacts of PRK with a 532 nm argon laser on endothelial cell parameters and corneal thickness. This was accomplished through a comparison of endothelial cell density (ECD), central corneal thickness (CCT) & and endothelial cell area coefficient of variation (CoV) utilizing specular microscopy before and following laser PRP treatment for PDR.

Patients and methods: This Prospective Clinical Study was done at the Ophthalmology Department, Al Azhar University Hospitals. The research involved 30 cases with PDR. Cases from either sex aged 35 years or older. Cases Diagnosed with PDR.

Results: In this research, we cleared that there was no statistically significant variance (p-value = 0.954) of CoV throughout the study. It was 33.4 ± 4.0 % before PRP, 33.7 ± 3.8 % after 1 week and 33.7 ± 3.8 % after 6 weeks. In this research, we illustrated that there was no statistically significant variance (p-value = 0.815) of CCT throughout the study. It was 517.8 ± 19 micrometres before PRP, 516.4 ± 18.8 micrometres after 1 week and 514.7 ± 18.5 micrometres after 6 weeks. We cleared that there were 8 patients (26.7%) with (6/12) BCVA, 10 patients (33.3%) with (6/18) BCVA, 9 patients (30%) with (6/24) BCVA and 3 patients (10%) with (6/36) BCVA in the studied patients.

Conclusion: Energy from an argon laser (523 nm) administered within the safe limits for PRP had no adverse impact on CCT or parameters related to the corneal endothelial cells.

Keywords

diabetic retinopathy; retinal photocoagulation; Argon laser

Subject Area

Ophthalmology

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