Document Type

Original Article


Background: The prevalence of ambulatory anorectal surgeries has been increasing, these procedures are deemed appropriate for day case surgery with the use of spinal anaesthesia. This study aims to compare the anaesthetic characteristics of intrathecal hyperbaric bupivacaine 0.5% and intrathecal hyperbaric prilocaine 2% in the context of elective anorectal surgery. Patients and Methodology: The research methodology used in this study is a prospective, double-blinded randomized approach. A total of eighty-eight patients were divided into two similar-sized groups, and randomly allocated to the trial. Group A, got intrathecal administration of 15 mg hyperbaric bupivacaine 0.5%, whereas group B, received intrathecal administration of 60 mg hyperbaric prilocaine 2%. Results: Group B demonstrated a more rapid initiation of sensory and motor block (with mean onset times of 1.86 minutes and 4.51, respectively), and a shorter duration time of sensory and motor block (mean of 120.8 and 105.3 min., respectively), compared to Group A that had a slower initiation period of both sensory and motor block (2.6 and 5.8 min., respectively), and prolonged duration time of sensory and motor block (197.79 and 161.1 min., respectively). Group A exhibited significantly longer time to first post-operative rescue analgesia, time to first post-operative voluntary voiding, and hospital stay duration. Conclusion: The utilization of hyperbaric prilocaine 2% resulted in a reduced duration of effect, with earlier recovery from sensory and motor blockade, early ambulation, voiding, and home discharge, thus reducing the overall hospital stay costs, and workload of medical staff.


Intrathecal; Hyperbaric; Bupivacaine 0.5%; Prilocaine 2%

Subject Area