Abstract
Background: Perforated peptic ulcers are a common surgical emergency requiring prompt intervention to avoid peritonitis and sepsis. Laparoscopic repair has become the standard approach, and various materials, such as cyanoacrylate glue, have been used to seal the perforation, aiming to improve outcomes and minimize complications.
Objectives: To evaluate the safety, efficacy, and outcomes of laparoscopic repair of perforated peptic ulcers using cyanoacrylate glue.
Patients and methods: Thirty-five cases with perforated peptic ulcers were treated laparoscopically using suturing combined with cyanoacrylate glue for reinforcement. The investigation has been performed from January 2022 to December 2023 at AL-Hussien University hospitals and military hospitals in Egypt. Patients were assessed for various preoperative and postoperative parameters, including age, sex, perforation size, operative time, complications, and recovery times.
Results: The study involved 35 patients with a mean age of 38.1 ± 8.1 years. The majority of patients had duodenal perforations (85.7%), with a mean perforation size of 5.1 ± 0.95 mm. The average operative time was 45 ± 9.5 minutes. Postoperatively, patients showed a reduction in pain scores and a quick return to normal activities. The overall complication rate was low, with 8.6% of patients experiencing chest infections and 5.7% developing leaks and peritonitis. Hospital stays averaged 3.44 ± 0.5 days, and patients resumed normal activities in a median of 9 days.
Conclusion: Laparoscopic management of perforated peptic ulcers using cyanoacrylate glue is a safe, effective, and minimally invasive alternative to traditional methods. The technique provides favorable outcomes with reduced operative time, faster recovery, and minimal complications. These findings suggest that cyanoacrylate glue could be a valuable addition to surgical options for treating perforated peptic ulcers.
Article Type
Original Article
Keywords
Peptic ulcer; laparoscopy; cyanoacrylate glue; surgical adhesives; gastrointestinal perforations
Subject Area
General Surgery
How to Cite This Article
Sultan, Ahmed Abd El Aal; Monier, Mohamed Ibrahim; Bayan, Ibrahim hamdy; and Sabek, Ahmed Ragab
(2025)
"Laparoscopic Management of Perforated Peptic Ulcer Using Cyanoacrylate,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
12, Article 2.
DOI: https://doi.org/10.58675/2682-339X.2835
