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Corresponding Author

Mahmoud Zakaria Mohamad Hamed Elshenawy

Authors ORCID

Role of L- Carnitine as Adjuvant Therapy with Letrozole for Ovulation Induction in Women with Polycystic Ovarian Syndrome (PCOS)

Document Type

Original Article

Abstract

Background: Acute respiratory failure patients who require life-sustaining supportive care may benefit from invasive mechanical ventilation. Numerous complications are also linked to it, which increases mortality and lengthens the time spent on the ventilator. It is crucial to remove the endotracheal tube (extubation) and free the patient from the ventilator as soon as possible because doing so is both safe and necessary. The best way to determine whether a patient is willing to wean is to use RSBI as a predictor of weaning success; this is done before weaning actually begins.

Aim and objectives: To evaluate the best cut-off value of rapid shallow breathing index (RSBI) to get the most successful extubation trial of mechanically ventilated patients, primary outcome: RSBI85 breath/minute/liter. As new cut-off value. Secondary outcome: detection failure of weaning.

Patients and methods: Over more than 24 hours, 47 adult patients requiring mechanical breathing were the subjects of this prospective observational study. The study was placed in the intensive care unit (ICU) at El-Hussein and Said Galal Hospitals, which are part of Al-Azhar University in Cairo, from March 2023 to March 2024. Evaluation of weaning using the RSBI for every patient in the study ≤85 If re-intubation is not necessary, it is considered a success; otherwise, it is referred to as a failure.

Results: By using RSBI as a predictor of weaning 85 breath/minute/liter. We achieved successful weaning in about 75% of the patients studied.

Conclusion: The study underscored the crucial importance of successful weaning and extubation by using RSBI as a predictor of weaning 85 breaths/minute/liter.

Keywords

Weaning; Mechanical Ventilation; Critical Care Unit

Subject Area

Anesthesiology, Emergency and ICU medicine

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