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Corresponding Author

Mahmoud Ahmed Mohamed Badawy

Authors ORCID

Role of L- Carnitine as Adjuvant Therapy with Letrozole for Ovulation Induction in Women with Polycystic Ovarian Syndrome (PCOS)

Document Type

Original Article

Abstract

Background: Polycystic ovary syndrome (PCO) is the most successive reason for anovulatory fruitlessness and hyperandrogenism in young females.

Aim: To explore the effect of circling against Mullerian chemicals on the result of various conventions of essential ovulation acceptance in females with polycystic ovary conditions.

Patients and Methods: The ongoing review enlisted 200 females with polycystic ovary disorder. The Department of Obstetrics and Gynecology at Al-Azhar University Hospital - Assiut served as the setting for the study. The review was conducted in a period somewhere in the range of 2020 and 2022.

Results: Ovarian reaction was recognized in a complete 160 (80%) patients, while different patients had no ovarian reaction, and the ovarian reaction bunch had a fundamentally lower antimullerian chemical in contrast with those with no ovarian reaction (3.33 ± 1.09 versus 7.90 ± 3.10 (ng/ml). Endpoint > 5.8 (ng/ml), the antimullerian chemical had 91.4% awareness and 97.4% explicitness with 95.5% by and considerable precision in forecast ovarian reaction to straightforward excitement. Notwithstanding, the ovarian reaction was equivalent either with letrozole or clomiphene citrate if antimullerian chemical under 5.7 ng/ml (90.9% versus 83.3%); however, the reaction with letrozole was altogether better compared to clomiphene citrate if there should be an occurrence of more elevated Level of antimullerian chemical surpassed 5.7 ng/ml (77.7% versus 62.5%).

Conclusion: Females with PCOS whose serum antiquarian chemical levels are highly elevated appear to be impermeable to essential ovarian registration and may require higher doses of this treatment. As a result, measuring serum concentrations of the antimullian hormone before treatment can be a valuable indicator of success and help choose the initial dose.

Keywords

Polycystic ovary syndrome; Antimullerian Hormone; hyperandrogenism

Subject Area

Obstetrics and Gynecology

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