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Corresponding Author

Mohamed Abd El Hamid Abd El Rahman Helal

Authors ORCID

Role of L- Carnitine as Adjuvant Therapy with Letrozole for Ovulation Induction in Women with Polycystic Ovarian Syndrome (PCOS)

Document Type

Original Article

Abstract

Background: One of the most prevalent clinical disorders in obstetrics is gestational diabetes mellitus (GDM).

Aim and objectives: To evaluate the relationship between fetal heart rate monitoring and umbilical fetal middle cerebral artery Doppler vs fetal outcome in pregnant women with GDM.

Patients and methods: This prospective study was conducted at the Al-Sayed Galal and EL-Hussein hospitals. From March 2021 to March 2022, one hundred patients with gestational diabetes mellitus were included in the study group. Two groups of patients were formed: Group A: Normal UA Doppler control group, and Group B: Doppler abnormalities in the umbilical arteries.

Results: The middle cerebral artery (MCA) doppler showed a statistically significant difference depending on gestational age between aberrant and normal. However, in terms of fetal weight, PH, Apgar l-min, Apgar 5-min, and gestational age (GA) at birth, there was no statistically significant difference between abnormal and normal UA Doppler readings. Additionally, all outcome measures, such as PH<7.2, Apgar at 1 minute<4, Apgar at 5 minutes<7, and infant death when the CTG was aberrant (P-value<0.005), were significantly reflected by the cardiotocograph (CTG.

Conclusion: The UA Doppler measurement had no bearing on fetal outcome measures such as neonatal PH, the 5-minute Apgar score, or neonatal death in patients with GDM. The Apgar score at one minute was the sole outcome measure that an aberrant UA Doppler impacted; however, MCA Doppler was significant for all outcome metrics, except the Apgar score at five minutes.

Keywords

Umbilical fetal; Middle cerebral arteries Doppler; Fetal heart rate; Gestational diabetes mellitus

Subject Area

Obstetrics and Gynecology

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