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Corresponding Author

Tarek Ibrahim Ahmed Abo Elfadl

Document Type

Original Article

Abstract

Background: Hemodialysis is considered a chronic inflammatory state with multiple causes. Chronic inflammation is a significant part of the pathophysiology of several cardiovascular diseases (CVDs).

Purpose: To evaluate the accuracy with which the neutrophil-to-lymphocyte ratio predicts cardiovascular risk in hemodialysis patients.

Patients and Methods: This study is a cross-sectional investigation involving 60 individuals undergoing hemodialysis. Every patient got a comprehensive assessment, which included gathering medical history, physical examination, and performing laboratory tests such as measuring the neutrophil-to-lymphocyte ratio. Additionally, cardiac evaluation was carried out using electrocardiography (ECG) and echocardiography. Patients were categorized into groups based on the occurrence of cardiovascular events.

Results: A cardiovascular incident occurred in over 80% of hemodialysis patients. Left ventricular hypertrophy was the most reported cardiovascular event, followed by global hypokinesia and reduced ejection fraction. Mild mitral regurge and mild tricuspid regurge were the commonest valvular lesions. Hypertension, hypercalcemia, reduced lymphocytic ratio, and the neutrophil-to-lymphocyte ratio showed statistical significance as predictors for cardiovascular diseases among hemodialysis patients.

Conclusion: Cardiovascular disease (CVD) is common among hemodialysis patients, especially Left ventricular hypertrophy (LVH), wall motion abnormalities, and reduced ejection fraction. The neutrophil-to-lymphocyte ratio had good prognostic accuracy in predicting cardiovascular diseases among hemodialysis patients.

Keywords

Neutrophil Lymphocyte Ratio; Cardiac Dysfunction

Subject Area

Internal Medicine

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