Abstract
Background: Postpartum haemorrhage (PPH) is severe bleeding following giving birth. It is a serious and risky condition.
Aim: To compare misoprostol, Carbetocin, and Oxytocin for prophylaxis of postpartum bleeding in the high-risk cases of CS.
Patients and methods: This prospective comparative research was done on cases admitted to the Obstetrics & Gynecology department at Al-Azhar University hospitals of Assuit and Luxor International Hospital in the period from 2022 to 2024.
Results: There significant variances were observed among groups in terms of procedures, for example, ergometrine, uterine artery ligation, compression sutures, hysterectomy, and blood transfusion. Post-operatively p<0.05, their insignificant variations were observed in haemoglobin (g/dl) or hematocrit value among groups p>0.05. Also, there significant variances were observed among groups in terms of abdominal pain, heat sensation, shivering, metallic taste, fever, headache, palpitations, nausea, vomiting, pruri p<0.05, but insignificant variance was discovered in headache, nausea, vomiting, and pruri p>0.05.
Conclusion: Carbetocin is a more effective treatment for preventing atonic postpartum haemorrhage in caesarean delivery patients who have high-risk characteristics. It requires fewer uterotonic medicines or surgical hemostatic measures in comparison to Oxytocin and misoprostol. Additionally, Carbetocin produces sustained uterine tetanic spasm throughout and following delivery.
Article Type
Original Article
Keywords
Carbetocin; Misoprostol; Oxytocin; Postpartum Hemorrhage; High-Risk Patients
Subject Area
Obstetrics and Gynecology
How to Cite This Article
El-Katatny, Hossam Hasan; Hussein, Mohamed Saleh; and Abd El-Latif, Islam Ahmed Iraqi
(2024)
"Carbetocin, Misoprostol and Oxytocin Uses in Prophylaxis of Postpartum Hemorrhage in High-Risk Patients: Prospective Hospital-Based Study,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
10, Article 46.
DOI: https://doi.org/10.58675/2682-339X.2727
