Document Type
Original Article
Abstract
Background: Conventional and laparoscopic surgery can impact a patient's immune status. Laparotomy causes more tissue trauma, while laparoscopy uses more cauterization, making both procedures potentially dangerous for the immune system.
Aim and objectives: To compare both laparoscopic and open ovarian cystectomy regarding their immunological consequences on ovarian tissue by assessing the production of antiovarian and antinuclear antibodies.
Patients and methods: This quasi-experimental clinical trial was conducted on 80 women aged ranged from 18 – 40 years who presented with ovarian cysts and were categorized into two groups: Group (1): (Laparotomy group): Involved 40 women who underwent open ovarian cystectomy and Group (2): (Laparoscopic group): Included 40 women, underwent for laparoscopic ovarian cystectomy.
Results: Insignificant variance among the two groups was observed according to the development of tumor markers and regarding Antinuclear Antibodies (ANA) and Anti-Ovarian Antibodies (AOA) development before ovarian cystectomy and 1, 3 months after ovarian cystectomy (P-Value 0.632). A significant variance was observed among tumor markers (CA125) and types of ovarian cysts by ultrasound (P-Value 0.045) (66.7% of patients had multilocular cysts by U/S associated with positive CA 125).
Conclusion: Both methods of removal of ovarian cysts, either laparoscopy or conventional laparotomy, do not affect the immune system and are not associated with developing antiovarian and antinuclear antibodies.
Keywords
Ovarian cyst; laparotomy; laparoscopic ovarian cystectomy
Subject Area
Obstetrics and Gynecology
How to Cite This Article
Olama, Magdy Abd El Mohsen; El Kafrawy, Mona Alsayed; and Mohammed, Sarah Hosney
(2024)
"Immunological Impact of Ovarian Cystectomy in Cases of Laparscopic Procedure and Conventional Laparotomy,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
10, Article 24.
DOI: https://doi.org/10.58675/2682-339X.2705
