Document Type

Original Article


Background: As an alternative to invasive Fundus fluorescein angiography) FFA), Optical coherence tomography angiography (OCT-A) can be used to scan chorio-retinal vasculature. Aim: Research OCT-A for sings of choroidal neovascularization (CNV) and its unique structure. In order to detect any current CNV activity, OCT-A can be used. Determine the sensitivity of OCT-A for detecting CNV activity and compare it with FFA and spectral-domain optical coherence tomography (SD- OCT). Patients and Methods: Thirty eyes with various sources of CNV diagnosis were enrolled in this prospective study to compare OCT-A, SD- OCT and FFA. Study was conducted at Al-Azhar University Hospitals and Tanta Ophthalmology hospital Egypt. Results: Clinically, OCT-A shows active state was linked to the presence of characteristics such as a sea-fan or medusa-shaped lesion, extensive branching and numerous microscopic capillaries, anastomoses or loops and perilesional dark halo in comparison to FFA and SD- OCT, OCT-A provides a reliable tool for detecting CNV. Conclusion: Because of its excellent sensitivity and specificity, OCT-A is a useful technique for diagnosing CNV in individuals with neovascular age-related macular degeneration (nARMD) who have not yet begun treatment. OCT-A could become an alternative to FFA in routine clinical practice.


choroidal neovascularization; Optical Coherence Tomography Angiography; Fundus fluorescein angiography.

Subject Area