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Document Type

Original Article

Abstract

Background: Any imaging method that is now available can be used to diagnose malignancies that originate in the bones. Plain radiography is the imaging modality that is utilized the vast majority of the time in order to arrive at a diagnosis and identify the characteristics of a variety of osseous lesions. The diagnosis of bone cancer can be challenging, but CT scans can provide useful information about the anatomical breadth of the disease. Magnetic resonance imaging (MRI) is the test that is considered to be the gold standard when it comes to diagnosing cancer and anomalies in the skeleton that are similar to tumors.Aim and objectives: to evaluate the utility of adding DW-MRI with ADC value measurements to differentiate between benign and malignant bone lesions, as well as tumor-like localized bone lesions, using histological correlations or a final clinical diagnosis as the reference gold standard. Subjects and methods: In a study that was carried out at the Assuit Hospital affiliated with Al-Azhar University, the Radio-Diagnosis Department enlisted the participation of fifty patients who were thought to have a localized bone lesion. Results:The comparison of the average ADC values of malignant and benign lesions revealed a discrepancy that was statistically significant. Concerning the ADC, it was not possible to differentiate between cancerous and benign lesions on the basis of statistical significance. As a result of any disorder that disrupts or replaces the normal microarchitecture of bony trabeculae and fatty marrow, there is an increase in the amount of free water flow, along with a larger ADC when compared to the marrow that is next to the affected area. This is true for BTs of both benign and malignant varieties.

Keywords

DW-MRI, bone tumors, tumor like focal lesions

Subject Area

Radiology & Radiodiagnosis

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