Document Type
Original Article
Abstract
Background: Despite early acclimation, there is an imbalance in systemic circulation and vasoactive factors. Failure of trophoblast invasion owing to risk, genetic polymorphism, and other factors inhibits the physiological remodeling of spiral arteriolar walls. Doppler demonstrates hemodynamic changes associated with PE. Ultrasound detects 75% of instances of preterm preeclampsia. In PE, PI, RI, and EDN indicate a maternal vascular disease. Failure of trophoblast invasion is caused by a persistent early diastolic notch or uneven blood flow velocity. VEGFs influence the placental development of HCG. Signs of preeclampsia include high or low HCG levels. Aim: to assess the role of first Trimistric Uterine Artery Doppler & maternal Serum Beta Human Chorionic Gonadotropin (HCG) in prediction of Preeclampsia. Subject and Methods: One hundred pregnant women participated in this prospective observational study at Al-Hussien university hospital between May 2021 and October 2021. Results: Comparison of urine protein mg/day in the first and second trimesters and Relation among cases who developed preeclampsia with Uterine artery Doppler indices in the first trimester showed statistically significant differences between study groups for validity (AUC, sensitivity, specificity). High PI pulsatility index and resistance index (RI)in the mother's uterine artery, as well as low β-HCG levels in the first trimester, were associated with preeclampsia.
Keywords
Human chorionic gonadotropin; Uterine Artery Doppler; Preeclampsia
Subject Area
Obstetrics and Gynecology
How to Cite This Article
Zakria, Abdel Monam Mohamed; Saeed, Ahmed Mohamed; and Elsayed, Alaa Elsayed Abo El Gheit
(2023)
"Role Of First Trimistric Uterine Artery Doppler And Maternal Serum Beta Human Chorionic Gonadotropin In Prediction Of Preeclampsia,"
Al-Azhar International Medical Journal: Vol. 5:
Iss.
1, Article 13.
DOI: https://doi.org/10.58675/2682-339X.2185
