Evaluation of Thyroid Hormones Level in Chronic Kidney Disease Patients

Authors

Mustafa Mahmoud Mohamed Alsagheer, M.B.B.CH - Resident Physician at Internal Medicine Department, Assiut Faculty of Medicine, Al-Azhar University, Cairo , Egypt.Follow
Ayman Abdel.Azeez Abdel. Rahman, Assistant professor of Internal Medicine, Assiut Faculty of Medicine, Al-Azhar University, Cairo , Egypt.
Mona Mohamed Abdelmeguid, Assistant professor of clinical pathology department, Assiut Faculty of Medicine, Al-Azhar University
Abdelhamed Abdelrazik Abdelhafez, Lecturer of Internal Medicine , Assiut Faculty of Medicine, Al-Azhar University, Cairo , Egypt.

Document Type

Original Article

Abstract

Background - Chronic-kidney disease is a global issue worldwide. The hypothalamus-pituitary-thyroid axis, peripheral-circulation, and production of thyroid-hormone release/or excretion are all affected by the etiology of thyroid dysfunction in CKD patients.

Aim - to measure the levels of TSH, T3, T4, in CKD patients.

Patients and Methods - The control group in this study, which included sixty CKD patients from Egypt, consisted of thirty healthy volunteers (subjects without CKD). There were three groups of participants: Group (1) 30 patients with CKD in Group (2) 30 CKD patients on dialysis regularly; Group 3: 30 healthy people without CKD.

Results - There was no age-related difference between the studied groups that was statistically significant (p-value greater than 0.05). Compared to female patients with CKD ESRD (8 patients, 26.7%) in the conservative group (60%) and control group (18 patients, 60%). There was a significant (p-value 0.001) difference between the studied groups in Hb, urea, creatinine, TSH, FT3, FT3 status, and FT4 and FT4 status.

Conclusion - The prevalence of thyroid disorders was higher in the end stage of CKD than in the early stage, and it was higher in CKD patients on hemodynamic support than in healthy individuals.

Keywords

Chronic Kidney Disease; Thyroid Stimulating Hormone; Hemodialysis; End-Stage; Early-Stage

Subject Area

Internal Medicine

How to Cite This Article

Alsagheer, Mustafa Mahmoud Mohamed; Rahman, Ayman Abdel.Azeez Abdel.; Abdelmeguid, Mona Mohamed; and Abdelhafez, Abdelhamed Abdelrazik (2023) "Evaluation of Thyroid Hormones Level in Chronic Kidney Disease Patients," Al-Azhar International Medical Journal: Vol. 4: Iss. 9, Article 9.
DOI: https://doi.org/10.58675/2682-339X.2011