Document Type
Original Article
Abstract
Background: A comparatively recent and quickly developing method of resolving human reproductive issues involves externalizing the human ovum with spermatozoa and transporting the generated embryo to the woman's uterus. The 1970s saw the publication of the first findings of implantations and pregnancy after the application of this technology in humans. Since then, the procedures recognized as in vitro fertilisation (IVF) and embryo transfer (ET) have led to multiple pregnancies, new knowledge about gametes interactions, and earlier embryogenesis progress. Unfortunately, compared to the therapy of tubal factor infertility, IVF is typically less effective for treating male factor infertility.
Aim of the Work: To assess the relation between follicular fluid AMH, oocyte maturation, fertilization and emberyo grading.
Patients and Methods: The current prospective cohort study was carried out on 85 infertile women with unexplained infertililty recruited from Ain Shams University Maternity Hospitals (ART unit) assisted reproductive technology unit, undergoing ICSI (intracytoplasmic sperm injection). During the period between December 2018 to December 2021.
Results: FF AMH with cut-off value >1.2 ng/ml could be used as single independent factor for prediction of successful fertilization. FF AMH associated with MII oocyte was significantly higher compared with GV, MI oocyte, with p-value3.4 ng/ml could be used as single independent factor for prediction of production of MII Oocytes. FF AMH level associate grade I embryo was significantly higher compared with grade II-IV, with p-value 0.006. FF AMH with cut-off value >4 ng/ml could be used as single independent factor for prediction of grade I embryo.
Conclusion: Our findings suggest that FF AMH density and fertilization, oocyte maturation, and embryo quality are positively correlated. As a result, we can use the FF AMH value as a predictor of the success of IVF.
Keywords
Follicular Fluid Anti-Müllerian Hormone, Oocyte Maturation, Intracytoplasmic Sperm Injection
Subject Area
Obstetrics and Gynecology
How to Cite This Article
Zakaria, Abdelmonem Mohamed; Saeed, Ahmed Mohamed; and Roshdy, Ahmed Abdelbaky
(2023)
"The Relation between Follicular Fluid Anti-Müllerian Hormone (AMH), Oocyte Maturation and Embryo Development in Intracytoplasmic Sperm Injection (ICSI) Cycles,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
9, Article 14.
DOI: https://doi.org/10.58675/2682-339X.2037
