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Document Type

Original Article

Abstract

Background : Chronic kidney disease (CKD) is an irreversible and slowly progressive disease. Patients with CKD commonly experience pruritus, especially those undergoing hemodialysis.

Aim of the work: identify the effect of uremic pruritis on the QoL of patients with CKD undergoing hemodialysis.

Method : This cross-sectional study included a sample size of 100 patients which was calculated with a power of 95%. We used three different tools for data collection; a structured interview Questionnaire, 5-D Itching scale (5-D IS), and Dermatology Life Quality Index (DLQI).

Results: Our study included 100 patients with CKD undergoing hemodialysis. The mean age of the patients was 48.18 ± 14.26yrs. 72% of the patients were males, and 28% were females. There was a significant association between the degree of pruritis and hemodialysis sessions, hemodialysis vintage, and degree of dermatology QoL index, P-value = 0.0001. Also, the length of pruritis and level of dermatology had a statistically significant correlation. QoL index, P-value = 0.0001. Additionally, there was a significant positive association (r = 0.93 and P-value = 0.0001) between the quality-of-life score and the pruritus score. which means that the higher the value of the pruritis score the worse the QoL.

Conclusion : Uremic pruritus is a symptom that negatively affects QoL end-stage renal disease patients, and the clinician must consider this during the treatment of those patients.

Keywords

Uremic pruritus, Chronic kidney Disease, QoL

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