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Corresponding Author

Amir Eid Mahmoud

Document Type

Original Article

Abstract

Introduction: In the US, 6-7% of pregnancies are complicated with diabetes mellitus (DM). It is divided into gestational diabetes (DM) and pre-gestational diabetes (PGDM) (GDM).Aim: The study's objective was to evaluate how pregestational diabetes mellitus affected foetal middle cerebral and umbilical arteries.Doppler indicators to identify potential negative neonatal outcomes. Patients and methods: The El Galaa Teaching Hospital and Al Hussien Hospital both participated in this comparative cross-sectional study. The current study included 120 patients, divided into two groups, who travelled to Al Hussien Hospital and El Galaa Teaching Hospital between October 2021 and the study's conclusion. Study group and the control group: 60 healthy pregnant women who were part of the control group (Group 1).Group 2 of the study included 60 expectant mothers who have gestational diabetes.

. Results: The managed group (RI 0.62 & PI 0.92) and the uncontrolled group did not statistically differ in the mean resistance index (RI) and pulsatility index (PI) of the umbilical artery (RI 0.62 & PI 0.92). The managed group's middle cerebral artery mean RI and PI (RI 0.81 and PI 1.77), compared to the uncontrolled group, did not statistically differ from one another. Conclusion: Maternal diabetes mellitus has no connection to abnormal Doppler indices of placental or foetal circulation (regardless the glycemic control).Additionally, the UA and MCA tests' sensitivity in predicting a poor neonatal outcome was only moderate.

Keywords

Middle Cerebral Artery; Umbilical Artery Doppler; Pre-gestational; diabetic; Pregnancies; Neonatal; Outcome

Subject Area

Obstetrics and Gynecology

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