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Document Type

Original Article

Abstract

Background: Pre-eclampsia (PE) is characterized by edema, proteinuria, and hypertension (≥0.3 g/24 h of protein in the urine (1+ dipstick) on two separate occasions, spaced ≥six hours apart). It complicates 2% to 8% of pregnancies and is a significant source of maternal and neonatal illness and death. Eclampsia, diffuse intravascular coagulation, and the HELLP syndrome are among the side effects of PE. Fetal death and IUGR are risks to the fetus. Clinical research has linked low vitamin D levels to unfavorable pregnancy results because vitamin D is crucial throughout pregnancy. Aim: The study's objective is to assess the impact of cholecalciferol (vitamin D3) supplementation on preeclampsia prevention in expecting mothers with a history of preeclampsia. Subject and Methods: The Department of Obstetrics and Gynecology, Air Force Hospital, and Al-Hussein Hospital, Al-Azhar University, conducted this research. The 200 pregnant participants in this research were split into two groups. Results: Regarding Preeclampsia Recurrence, there was a substantial variation between the two study groups. Regarding the measures of vitamin D level, there was a very substantial variation between the two groups. Between the two study groups, there was no discernible change in the measures of serum ionized calcium. Conclusion: Worldwide, there is a significant prevalence of vitamin D insufficiency. Infants and pregnant women are more susceptible to vitamin D insufficiency. Prenatal vitamin D supplementation treatment may assist in lowering the prevalence of preeclampsia/gestational hypertension.

Keywords

Cholecalciferol, preeclampsia, Vitamin D.

Subject Area

Obstetrics and Gynecology

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