Document Type
Original Article
Abstract
Background; The pre-operative stage is an important frustrating process for almost all patients who need operations, especially children. As a consequence, an anesthesiologist's first concern involves reducing patient stress prior to surgery, Aim and objectives; the aim of this study was to make a comparison between the impact of intranasal dexmedetomidine versus intranasal midazolam in prevention of pre-operative anxiety in children group undergoing tonsillectomy. Subjects and methods: The current study is a randomized clinical trial carried out at department of Anesthesia and Intensive Care and pain management, Al-Azhar faculty of medicine. Seventy-five children aged 5-10 years, of either sex, BMI between 5th and 85th percentile for age, with American Society of Anesthesiologists (ASA) physical status (1) and undergoing elective tonsillectomy under general anesthesia Patients were categorized into three equal groups (twenty-five each): Group C: Control group (n=25) received intranasal 2 ml normal saline 45 minute before surgery. Group D: Dexmedetomidine Group (n = 25) received intranasal dexmedetomidine at a dose of 1 μg/kg in 2 ml volume 45 minute before surgery. Group M: Midazolam Group M (n = 25) received intranasal midazolam at a dose of 0.2 mg/kg in 2ml volume 45 minute before surgery. Results; there was no statistically significant difference between the studied groups as regard heart rate and Separation Score. Conclusion: When compared to intranasal midazolam 0.2 mg/kg, pre-medication with intranasal dexmedetomidine 1 ug/kg was linked with lower drowsiness and discomfort rates and simpler child parent separation. Additionally, all medications were equally successful in lowering the child's anxiety using Separation Score: Intranasal dexmedetomidine seems to offer some advantages compared with midazolam. Thus, it can be used effectively and safely as a pre-anesthetic medication in children undergoing any surgical procedures under general anesthesia.
Keywords
dexmedetomidine, intranasal, midazolam, pre-anesthetic medication
Subject Area
Anesthesiology
How to Cite This Article
AbdElnaby, Ahmed Mahmoud Mohammed; Ezza, Hamed Ahmed Sanad Al; and Kumity, Ali Abdallah Al
(2023)
"Prevention of pre-operative anxiety in pediatric tonsillectomy using intranasal dexmedetomidine versus intranasal midazolam,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
6, Article 34.
DOI: https://doi.org/10.58675/2682-339X.1864
