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Document Type

Original Article

Abstract

Background: Central nervous system (CNS) defects are the most frequent malformations and can be detected with conventional prenatal ultrasonography (US). 3D imaging allows for the simultaneous assessment of the foetal central nervous system in three orthogonal planes, better defining the spatial relationship of CNS components and abnormalities.

Objective: The value of traditional 2D and modern 3D ultrasound in the diagnosis of CNS anomalies during the second trimester of pregnancy (18-22 weeks of gestation) is evaluated, and the importance of foetal neurosonogram in the detection of CNS anomalies is highlighted.

Methods: This was a prospective descriptive study, conducted at Al-Hussein and Bab El-Sheirya (Sayed Galal) Hospitals, Al-Azhar University on 40 pregnant females with CNS anomalies who were examined and evaluated sonographically. They came for routine antenatal screening or for confirmatory advice from another place during the period from November 2021 to May 2022.

Results: There was no statistically significant difference between 2D and 3D ultrasonography in detection of all studied fetal CNS anomalies. The sensitivity of 2D was 83.33%, specificity was 62.5%, and accuracy was 80% and the sensitivity of 3D was 88.09%, specificity was 71.8%, and accuracy was 85.5%.

Conclusion: This study concluded that conventional 2D had a comparable and accurate screening and diagnostic validity in diagnosis of CNS anomalies during the second trimester of pregnancy compared with modern 3 D ultrasound.

Keywords

Ultrasonography; Two-dimensional; Three-dimensional; Central Nervous System Anomalies; Second Trimester

Subject Area

Obstetrics and Gynecology

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