Document Type
Original Article
Abstract
Background: Epilepsy is a brain disorder characterized by recurrent attacks of seizures. A seizure is a sudden change of behavior due to a transient alteration in the electrical pattern of the brain. Since despite appropriate drug treatment, one-third of patients continue to have seizures, other treatment must be considered. Aim: This study aims at emphasizing the importance of epilepsy surgery in pediatrics by assessing surgical outcome as regard seizure freedom and surgical morbidity & mortality at Al-Azhar university hospitals.
Patients and Methods: Prospective and retrospective study on 27 pediatric patients diagnosed as drug resistant epilepsy, with 6 months to 1 year follow up at least. Group A,14 cases operated by corpus callosotomy, Group B, 10 cases underwent lesionectomy, and Group C, 3 cases underwent MST. Result: 15 cases become seizure free, and 6 cases have rare disabling seizure. Lesionectomy was better than corpus callosotomy in achieving seizure freedom, In Group A, 4 cases become seizure free in comparison to 9 cases in group B. 11 cases of patients in group A (78.6%) showed increase alertness in comparison to the clinical mentality before surgery. The complications that have occurred were transient and resolved shortly. Conclusion: Epilepsy surgery in childhood is effective & safe and needs to be done early to prevent cognitive delay. Even when complete seizure freedom is not achieved, a great decrease in frequency of seizures and number of AEDs is a remarkable result.
Keywords
Seizure outcome; drug resistant epilepsy; lesionectomy; Palliative.
Subject Area
Neurosurgery
How to Cite This Article
Hammouda, Mohammed Refaat Mohammed; El Khadrawy, Shehab M.; Mansour, Mohamed Hasan; Hassan, Alaa Rashad Ibrahim; and Rabei, Alazzazi
(2023)
"Outcome of epilepsy surgery in pediatrics,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
6, Article 1.
DOI: https://doi.org/10.58675/2682-339X.1835
