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Corresponding Author

Naeem Saad Mohey El-Din Mahmoud Al-Jamal

Document Type

Original Article

Abstract

Background: It might be dangerous and further obstruct the surgical field to have intraoperative bleeding during endoscopic sinus surgery (ESS). Tranexamic acid may be able to reduce bleeding during surgery. Aim: assess the effect of topical TXA and hydrogen peroxide solution on bleeding and improvement of surgical field during FESS in patients with chronic sinusitis with or without sino nasal polyposis. Patients and methods: 30 patients were included, for all the 30 patients, Pads soaked with TXA 5% was introduced in one side of the nasal cavity for 10 minutes then irrigation by 3% hydrogen peroxide solution which was freshly prepared by a 50% dilution with a physiological saline solution. The other side of the nasal cavity was not receive pads of TXA nor H2O2 and was only on controlled blood pressure during the operation. Result: There was statistically significant difference between both sides with time reduced in applied side after the application of tranexamic acid and H2O2 wash regarding surgical field by Boezaart grading ,but it is non-significant in control side. There were statistically significant differences according to blood loss between both sides of the nose after application of tranexamic acid and H2O2 wash either after 15 minutes ,30 minutes, and 45 minutes . Conclusion: The application of topical TXA with the irrigation with 3% H2O2 may be a useful method for providing a suitable surgical field.

Keywords

tranexamic acid; H2O2; Endoscopic Sinus Surgery

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